鼠疫 — meaning in English

shǔ yì

English meaning

murrain noun Infectious disease; pestilence, plague; (countable) sometimes used in curses such as a murrain on someone: an outbreak of such a disease; a plague.
pest noun An insect or animal that damages crops, spreads disease, or is otherwise harmful.
plague noun A deadly, fast-spreading disease, especially historically the bubonic plague.

鼠疫 is used for these senses in English:

Pest The corresponding part of the current-day city of Budapest, on the eastern side of the Danube.
murrain (countable, veterinary disease, chiefly, historical) Any of several highly infectious diseases of cattle or other livestock, such as anthrax, babesiosis, or rinderpest; or a particular epizootic thereof; also, an infectious disease affecting other animals, such as poultry.
plague (often used with the, sometimes capitalized: the Plague) The bubonic plague, the pestilent disease caused by the virulent bacterium Yersinia pestis.

noun Infectious disease; pestilence, plague; (countable) sometimes used in curses such as a murrain on someone: an outbreak of such a disease; a plague.
noun A widespread affliction, calamity, or destructive influx, especially when seen as divine retribution; a plague.
noun Any of several highly infectious diseases of cattle or other livestock, such as anthrax, babesiosis, or rinderpest; or a particular epizootic thereof; also, an infectious disease affecting other animals, such as poultry.
noun An infectious disease affecting plants.

noun An insect or animal that damages crops, spreads disease, or is otherwise harmful.
noun An annoying person, especially one who keeps bothering others.