noun

NGF

en-jee-EF

NGF (noun) means a protein that keeps certain nerve cells alive, encourages them to grow and directs the sprouting of their fibres; short for nerve growth factor. Example: “Levels of NGF rise sharply at the site of an injury.”

noun

technical A protein that keeps certain nerve cells alive, encourages them to grow and directs the sprouting of their fibres; short for nerve growth factor.

"Levels of NGF rise sharply at the site of an injury."

"The lab studies how NGF influences pain signalling in the skin."

marketing In consumer products and cosmetics marketing, an ingredient or treatment claimed to mimic or stimulate nerve growth factor.

"The serum is sold on an NGF claim that has little clinical backing."

How to Use NGF

Learner’s notes

In plain EnglishA natural substance in the body that helps nerve cells grow and stay alive.

When to use it

Almost always written as the initialism in scientific and medical writing; spell it out on first use for a general audience.

Memory tip

Say the three letters separately: N-G-F.

Trace the full origin ↓

Easily confused with

BDNF EGF VEGF

Common pairings

NGF signalling anti-NGF therapy NGF receptor serum NGF levels

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Levels of _____ rise sharply at the site of an injury.

Etymology

An initialism of nerve growth factor.

Origin: English

Synonyms

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nerve growth factor neurotrophin

Frequently Asked Questions

What does NGF stand for?

Nerve growth factor. It is one of a family of proteins called neurotrophins, which support the survival and growth of nerve cells.

What is the difference between NGF and BDNF?

Both are neurotrophins, but they act on different populations of neurons. NGF mainly supports sensory and sympathetic neurons in the peripheral nervous system, while BDNF (brain-derived neurotrophic factor) acts more widely in the brain and is associated with learning and memory.

Is NGF linked to pain?

Yes. NGF sensitises pain-carrying nerve fibres, and drugs that block it have been trialled as painkillers for conditions such as osteoarthritis.

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Vocabulary lists that include NGF:

Words That End With F