A vein is a blood vessel, or a thin streak running through a material like marble or wood, and it can also describe a style or mood running through a piece of writing. A vane is a device that turns to show wind direction, such as a weather vane, or the flat blade of a turbine. Blood runs through veins; wind turns a vane.
The core difference
Vein is about blood vessels, streaks, and running styles, while vane is about devices that catch or show the direction of wind or fluid.
- vein — a blood vessel: The nurse found a vein in his arm to draw blood.
- vein — a streak through a material: The countertop had grey veins running through the white marble.
- vane — a device showing wind direction: The weather vane on the barn swung around to point north as the front moved in.
How to tell them apart
Vein comes from Latin vena, meaning blood vessel, by way of Anglo-Norman veine. Vane has a completely different origin, from Old English fana, meaning cloth, banner, or flag — the same root that gave German its word Fahne. Early weather vanes really were flag-like devices before the familiar spinning arrow design took over.
A handy memory trick: vein has an e-i pair like the word receive, and it deals with something inside the body. Vane has an a, like a weathervane pointing at the sky. The confusion often shows up in weather writing or DIY articles, where a weather vein appears instead of a weather vane.